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Name: U-47700 (3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide)
Type: Synthetic opioid
AKA: U-47700
![U-47700 (3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide) image](https://grammasearch.com/dev/v2/img/synthopiod.png)
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
U-47700 is a synthetic opioid developed by Upjohn in the 1970s. It was intended for research and potential medical use but was never marketed. U-47700 gained notoriety as a designer drug in the 2010s, linked to numerous overdose deaths due to its potency. Its legal status has been updated in many countries to restrict its production and distribution.
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V. Legal Information
U-47700 is a synthetic opioid classified as a Schedule I controlled substance in the US. It is regulated due to its high abuse potential and health risks. Globally, it is similarly controlled under various national drug laws, with increasing restrictions reflecting the growing concerns about synthetic opioids and their impact on public health.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
U-47700, a synthetic opioid, is known for its potent analgesic effects. As a downer, it causes significant sedation and respiratory depression. Short-term effects include pain relief and euphoria, while long-term use can lead to severe addiction, tolerance, and overdose. Overdose risks include life-threatening respiratory failure. Safe use involves very careful dosing due to its high potency. Recent findings highlight its high abuse potential and the regulatory challenges associated with its misuse.  |
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VII. Psychological Effects
U-47700, a synthetic opioid, impacts opioid receptors, causing strong euphoria and sedation. Psychological effects include mood swings and impaired cognition. Effects last several hours, with risks of addiction and severe mental health issues. Ongoing research investigates its abuse potential and impact on mental health.
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VIII. Culture
U-47700, a synthetic opioid, gained attention in the mid-2010s due to its potency and association with numerous overdose deaths. It is part of the broader opioid crisis, highlighting the risks of synthetic opioids in the illicit drug market. The substance’s cultural impact is largely negative, associated with the dangers and challenges of unregulated synthetic drugs. U-47700 underscores the ongoing public health crisis related to opioid addiction and the continuous struggle to control and regulate synthetic opioids. It is a stark reminder of the evolving nature of drug abuse and the significant societal impact of opioid misuse.
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